We conclude that in this group of patients a PAWP higher than 18 mmHg is common. The pulmonary wedge pressure ( PWP) (also called pulmonary arterial wedge pressure ( PAWP ), pulmonary capillary wedge pressure ( PCWP ), pulmonary artery occlusion pressure ( PAOP ), or cross-sectional pressure) is the pressure measured by wedging a pulmonary artery catheter with an inflated balloon into a small pulmonary arterial branch. In a multivariate stepwise logistic regression model a persistently elevated PAWP (median >18 mmHg) was a strong predictor of mortality after correction for baseline differences (OR estimate 6.82 95% CI 1.66-37.81). Patients who met standard criteria for ARDS were more likely to develop a high PAWP. The mean maximum PAWP reading among patients was 22.5 mmHg (95% CI 21.2-23.8) and mean median was 16.6 mmHg (95% CI 15.6-17.5). Of 120 subjects 71 (59%) had a pulmonary artery catheter (44 at randomization, 27 later). Pulmonary artery catheters were inserted at the discretion of the attending physician, and PAWP was collected every 8 h when present. Patients with or at high risk of congestive heart failure were excluded from the original study.
Right ventricular pressure systolic 1530. Pressure range (in mmHg) Central venous pressure 38.
#PULMONARY ARTERY WEDGE PRESSURE MEANING TRIAL#
Post hoc analysis of 120 patients with or at high risk of ARDS, enrolled in a randomized controlled trial of pressure- and volume-limited ventilation. Distinctions between pulmonary artery pressure, pulmonary capillary wedge pressure, pulmonary venous pressure and left atrial pressure can be made.
In addition, to examine the effects of clinical variables on the presence of a high PAWP (>18 mmHg) and the effect of an elevated PAWP on mortality. To determine the incidence and severity of pulmonary artery wedge pressure (PAWP) elevation in patients with ALI/ARDS.
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